Mounjaro price changes explained
4.3/5
What are your options?
Stay on Mounjaro
Continue with current pricing
You can stay on your current Mounjaro treatment plan without making any changes. Our clinical team will review your order and confirm the best option for continuing your treatment safely.
Reorder MounjaroWegovy is an option
Unchanged pricing from £99.99
Wegovy is a GLP-1 treatment that helps reduce appetite and support long-term weight management. Our clinicians can help you decide which option best fits your goals and ongoing treatment plan.
Speak to us
Get support from our clinicians
If you’d like to discuss your options or have any questions, our medical team is here to help. Every consultation is reviewed carefully to ensure your treatment remains safe and effective.
Get in touchCompare cost and average weight loss
In anonymised MedExpress data, people prescribed Mounjaro lost an average of around 20% of their body weight after 12 months. Individual results vary.
Drag the slider to your start weight
105kg
After 12 months
Wegovy
Weight loss
16kg
Total cost
£2,709.88
Cost per kg
£169.37
Mounjaro
Weight loss
21kg
Total cost
£3,369.88
Cost per kg
£160.47
Wegovy vs Mounjaro
 Wegovy® (semaglutide) |  Mounjaro® (tirzepatide) |
|---|---|
Price range £99.99–£199.99 | Price range £179.99–£309.99 |
Average weight loss (in clinical studies)* 20.7% of body weight | Average weight loss (in clinical studies)* 22.5% of body weight |
Treatment schedule Weekly injection | Treatment schedule Weekly injection |
Dose adjustments Gradual, guided by your clinician | Dose adjustments Gradual, guided by your clinician |
Suitable for oral contraception? Yes | Suitable for oral contraception? No |
Injection site reactions (in studies)** Reported in 5% of participants | Injection site reactions (in studies)** Reported in 4.4% of participants |
Heart health indication*** Approved to reduce the risk of heart disease in adults with obesity or overweight and existing heart conditions | Heart health indication*** Not currently licensed for this use |
*Effectiveness: In 72 weeks, people taking Mounjaro 15mg in a clinical study lost an average of 22.5% of their body weight when taken as directed. This means that someone who weighs 100kg may lose an average of 22.5kg in 72 weeks (1 year, 5 months).
In 72 weeks, people taking Wegovy 7.2mg in a clinical study lost an average of 20.7% of their body weight when taken as directed. This means that someone who weighs 100kg may lose 20.7kg on average in 72 weeks (1 year, 5 months).
These are examples only and not a prediction of individual results.
**In SURMOUNT-1, the pooled average for injection site reactions from 2,539 participants was 4.4% with Mounjaro. For Wegovy, this was 5.0% in the STEP-1 clinical trial of 1,961 participants.
***Heart health: Clinical trials show Wegovy can reduce the risk of heart attack, stroke and death from heart disease by up to 20% in people with obesity or who are overweight and have existing heart disease, even if they don’t have diabetes.
About switching weight loss medications
You don’t need to start over. Our clinicians can help find you a suitable Wegovy dose based on your current Mounjaro dose and tolerance.
Mounjaro and Wegovy work differently in the body, so their doses don't translate directly. There isn't currently any published research that shows how to convert a dose from one treatment to another. Because of this, switching between them isn't about finding an "equivalent" dose. Instead, your prescriber focuses on:
- How you've responded to treatment so far
- How well you've tolerated it, particularly when it comes to side effects
- Your long-term goals and individual health profile
Everyone responds differently. If you switch from Mounjaro to Wegovy, you may need to start at a lower dose and build up again. Your MedExpress prescriber will explain your options and help you decide the best next step.
Switching FAQs
Switching medications is a normal and common occurrence — it’s something medical professionals recommend regularly for conditions like high blood pressure or high cholesterol, whether it’s to reduce side effects or lower costs.
However, you may not need to switch from Mounjaro, but instead explore a lower dose. We’ll work with you to find the solution that’s right for your needs, budget and goals.
For those who need a more cost-effective option, Wegovy offers similar weight-loss results and some additional benefits, including support for heart health. If you choose to switch, our clinicians will make sure the change is safe, smooth, and tailored to you. That way, you can keep moving towards your health goals with minimal disruption.
Both Wegovy (semaglutide 7.2mg) and Mounjaro (tirzepatide 15mg) are highly effective for long-term weight loss, but they work slightly differently and may affect people differently.
In 72 weeks, people taking Wegovy 7.2mg in a clinical study lost an average of 20.7% of their body weight when taken as directed. This means that someone who weighs 100kg may lose 20.7kg on average in 72 weeks (1 year, 5 months).*
In 72 weeks, people taking Mounjaro 15mg in a clinical study lost an average of 22.5% of their body weight when taken as directed. This means that someone who weighs 100kg may lose 22.5kg on average in 72 weeks (1 year, 5 months).**
These are examples only. It is not a prediction of individual results.
Both can be excellent options. The right choice comes down to your health needs, goals, lifestyle and how your body responds to treatment. Our medical team will help you find what works best for you.
*STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 7.2mg). Individual results vary.
**SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.
Wegovy and Mounjaro work in similar ways, so some people experience similar side effects. The most common are digestive effects such as nausea, vomiting, diarrhoea, constipation and stomach discomfort.
Side effects are usually mild to moderate and often improve as your body adjusts to treatment.
If you tolerated Mounjaro well, you may have a similar experience on Wegovy. However, everyone responds differently depending on the dose and individual factors. Your clinician will review your health and treatment history before switching, to help you move safely and comfortably.
A note about the higher Wegovy 7.2mg doseThe highest dose of Wegovy (7.2mg) can sometimes cause a temporary side effect called dysesthesia. This can feel like tingling, pins and needles, buzzing, or a mild burning sensation on the skin. It is not nerve damage and usually improves over time, even while continuing treatment.
In clinical studies:
- Around 7 in 10 people reported digestive side effects
- Around 1 in 4 people reported dysesthesia
- Around 1 in 20 people stopped treatment due to side effects
Most side effects were mild to moderate and settled over time. Your care team will monitor your response closely and can adjust your dose if needed to help manage side effects and keep your treatment safe and comfortable.
In some cases, we may recommend a lower starting dose to maximise comfort and minimise side effects during the switch. This isn't a step backwards — it's a clinically safe way to help your body adjust while keeping progress on track.
Our aim is always steady, sustainable weight loss without compromising tolerability.
Mounjaro (tirzepatide)
- Mimics two naturally occurring hormones in the body (GIP and GLP-1)
- Uses a wider range of doses (up to 15mg)
Wegovy (semaglutide)
- Mimics one hormone (GLP-1)
- Uses a different range of doses (from 0.25mg to 2.4mg)
Another way to think about it is like driving two different cars.
Wegovy is a car with a set number of gears, and you move up through them gradually as your body adapts.
Mounjaro is a different car with more gears available, and those gears work in a different way because the engine is designed differently. You can't compare "third gear" in one car with "third gear" in another and expect the same speed or feel.
In the same way, Mounjaro and Wegovy have different dose ranges and work differently in the body. The same dose number does not mean the same strength, effect, or weight loss results.
More questions? See all FAQs
Your medical team
Dr Bryony Henderson
Dr. Bryony Henderson joins HeliosX as Medical Director for the UK and US, bringing extensive clinical operations, governance, and digital health experience from Kry/Livi and Numan. A recognised clinical voice, she has contributed to award-winning campaigns, published on health inequalities, and appeared across major national media. At HeliosX, she leads clinical governance and quality and supports the delivery of safe, innovative, scalable care.
Dr Adam Abbs
Adam is a doctor and advocate for increasing access to healthcare internationally. He has extensive experience in video consultations, technology-enabled examinations, remote biomarker testing, and education. He is a published author and has medical licenses in the UK, Spain and Republic of Ireland.
Dr Safia Hussain
Consultant GP and Quality Lead
MBBS, BSc, MRCGP, DRCOG, PGDip Clinical Dermatology
Safia is a GP with experience working in the NHS with a particular interest in diabetes and weight loss management. She is passionate about the power of digital healthcare and oversees our approach to patient safety and regulatory compliance.
Results that speak for themselves
Chloe J. after 2 months
Rosie G. lost 25kg after 6 months
Roisin S. lost 19.5kg after 3 months
Magdalena S. lost 22kg after 4 months
Natasha T. lost 29kg after 4 months
Premila C. lost 23kg after 4 months
These customers received compensation for sharing their experience.
The thing I like most is the aftercare. I get really helpful emails with tips and advice. After week one I’m 6lb down, so let’s see where it takes me on my weight loss journey.
Sonia, weight loss customer
Products are very effective. I’ve lost weight already in just 14 days so happy. Would recommend this company highly. In fact I’ve already introduced 3 people to MedExpress.
Shireen, weight loss customer
I am one week into treatment and feeling good — less cravings and fuller for longer in between meals. The website is really informative and ordering a straightforward process.
Mrs Roe, weight loss customer
I am having a good experience. No side effects presently. I love the feeling of not feeling hungry, it’s very calming for me. I am enjoying the journey so far.
Mr Gale, weight loss customer
Professional, quick to respond, quick delivery and the product has made me feel the most confident I have felt in years.
Claire, weight loss customer